Glycosylation of Hemagglutinin and Neuraminidase of Influenza A Virus as Signature for Ecological Spillover and Adaptation among Influenza Reservoirs
Glycosylation of the hemagglutinin (HA) and neuraminidase (NA) of the influenza provides crucial means for immune evasion and viral fitness in a host population.However, the time-dependent dynamics of each glycosylation sites have not been addressed.We monitored the potential N-linked glycosylation (NLG) sites of over 10,000 HA and NA of H1N1 subty